
R-410A, sold under brand names like Puron, is a hydrofluorocarbon (HFC) refrigerant blend that replaced R-22 as the standard for residential air conditioning systems starting in 2010. Unlike R-22, R-410A does not deplete the ozone layer. It operates at approximately 50% higher pressure than R-22, which enables more efficient heat transfer but requires components rated for higher pressures. R-410A has been the dominant residential AC refrigerant for over a decade. However, due to its high global warming potential (GWP), R-410A is now being phased down under the AIM Act, with R-454B designated as its primary replacement in new equipment starting in 2025.
/ˌɑːr fɔːr ˈtɛn eɪ rɪˈfrɪdʒərənt/
R-410A, sold under brand names like Puron, is a hydrofluorocarbon (HFC) refrigerant blend that replaced R-22 as the standard for residential air conditioning systems starting in 2010. Unlike R-22, R-410A does not deplete the ozone layer. It operates at approximately 50% higher pressure than R-22, which enables more efficient heat transfer but requires components rated for higher pressures. R-410A has been the dominant residential AC refrigerant for over a decade. However, due to its high global warming potential (GWP), R-410A is now being phased down under the AIM Act, with R-454B designated as its primary replacement in new equipment starting in 2025.
What is R-410A refrigerant?
R-410A is the standard residential AC refrigerant that replaced ozone-depleting R-22. It is being phased down for new equipment in favor of lower-GWP R-454B, but remains available for servicing existing systems.
Source: The Cooling Company

R-410A replaced R-22 and is now being phased down in favor of R-454B.
Most AC systems installed in Las Vegas homes between 2010 and 2024 use R-410A. These systems will continue to be serviced and recharged with R-410A for their full lifespan. The transition to R-454B affects only new equipment manufacturing — your existing R-410A system is not becoming obsolete, and refrigerant will remain available for service.
If you are buying a new AC system in 2025 or later, ask about R-454B compatibility. While R-410A systems are still being serviced, new R-454B equipment offers lower environmental impact and may qualify for additional rebates.
“If you are buying a new AC system in 2025 or later, ask about R-454B compatibility. While R-410A systems are still being serviced, new R-454B equipment offers lower environmental impact and may qualify for additional rebates.”
R-410A is actually a blend of two refrigerants: R-32 and R-125 in a 50/50 mix. This near-azeotropic blend behaves almost like a single substance, simplifying charging and service.
Is R-410A being phased out?
R-410A is being phased down for new equipment manufacturing starting in 2025. Existing systems will still be serviced with R-410A, and the refrigerant will remain available.
Is R-410A better than R-22?
R-410A does not deplete the ozone layer, operates more efficiently, and supports higher-SEER equipment. However, it has a higher global warming potential, which is why R-454B is next.
Can I add R-410A to an R-22 system?
No. R-410A operates at much higher pressures than R-22. Mixing them or using R-410A in R-22 equipment can cause dangerous system failures.
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